Androgen receptor activation by polychlorinated biphenyls

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Androgen receptor activation by polychlorinated biphenyls

The exposure to environmental endocrine disrupting compounds (EDC), as polychlorinated biphenyls (PCBs), widely diffused in the environment may produce epigenetic changes that affect the endocrine system. We found that PCBs activate AR transcriptional activity and that this effect is potentiated by the demethylase Jarid1b, a histone demethylase that catalyzes the removal of trimethylation of ly...

متن کامل

Biodegradation of Polychlorinated Biphenyls by and Isolated from Contaminated Soil

Polychlorinated biphenyls (PCBs) cause many significant ecological problems because of their low degradability, high harmfulness, and solid bioaccumulation.Two bacterial strains were isolated from soil that had been polluted with electrical transformer liquid for more than 40 years. The isolates were distinguished as Lysinibacillus macrolides DSM54Tand Bacillus firmus NBRC1530...

متن کامل

Neutrophil activation by polychlorinated biphenyls: structure-activity relationship.

Polychlorinated biphenyls (PCBs) rapidly stimulate polymorphonuclear leukocytes (neutrophils) in vitro to produce superoxide anion (O2-). This response results from activation of various intracellular signal transduction pathways and appears to occur in a structure-specific fashion. Individual PCB congeners, varying in pattern and extent of chlorination, were tested for their ability to stimula...

متن کامل

Polychlorinated Biphenyls

Polychlorinated biphenyls (PCBs) are industrial compounds with multiple industrial and commercial uses (Table 41.1). PCBs are chemically inert and stable when heated. These properties contribute greatly to PCBs having become environmental contaminants. The chemical inertness and heat stability properties that make PCBs desirable for industry also protect them from destruction when the products ...

متن کامل

Carcinogenicity of polychlorinated biphenyls and polybrominated biphenyls.

Monograph Working Group Members V J Cogliano (USA)–Chair; K Aronson, H Tryphonas (Canada); Y L Guo (Taiwan, China); M Machala (Czech Republic); E C Bonefeld-Jørgensen, K Vorkamp (Denmark) J P Cravedi, B Le Bizec, J F Narbonne (France); H Esch (Germany); P Cocco, F Merletti (Italy); R Vermeulen (unable to attend; Netherlands); A Agudo (Spain); N Johansson (Sweden); H Fiedler, N Hopf (Switzerland...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Epigenetics

سال: 2013

ISSN: 1559-2294,1559-2308

DOI: 10.4161/epi.25811